PREZERV
The fertility side of TRT

How to read your semen analysis (WHO 2021 reference values)

Updated July 14, 2026 · 5 min read

A semen analysis report is a wall of numbers with no context, and it's easy to spiral over one line. Here's what each value actually measures, the reference limits the labs use, and why a single result is never the whole story.

The reference limits (WHO 2021, 6th edition)

The World Health Organization's lower reference limits come from the 5th percentile of men who fathered a child within 12 months. Below them doesn't mean "infertile", it means you're below where most recently-fertile men sit, and worth a closer look.

Semen volume: 1.4 mL. Sperm concentration: 16 million per mL. Total sperm number: 39 million per ejaculate. Total motility: 42%. Progressive motility: 30%. Normal morphology: 4%. Vitality: 54% live. Those are the numbers your lab is comparing against.

What each one actually tells you

Concentration is sperm per mL; total count is concentration times volume, and is often the more meaningful figure. Motility is the share that are swimming, progressive motility (moving forward, not just twitching) is what matters most for reaching an egg.

Morphology is the share with a normal shape, and 4% normal is the reference limit, yes, that low is expected, so don't panic at a number like 5%. Volume that's very low can point to a collection or plumbing issue rather than production. Azoospermia means no sperm found at all.

Why one result isn't a verdict

Semen parameters are genuinely noisy, they swing with abstinence time, a recent illness or fever, stress, and even how the sample was collected and handled. A single low result is a reason to retest, not a diagnosis.

Most clinicians want at least two samples a few weeks apart before drawing conclusions. And because sperm take about 2.5 to 3 months to be produced, a test only reflects what your body was doing months ago, so retesting two weeks after a change tells you nothing.

Getting a clean sample

For a representative result, labs generally ask for 2 to 7 days of abstinence beforehand, not zero, not two weeks. Keep the sample near body temperature and get it to the lab quickly, since sperm degrade when it sits or cools.

If a result is off, ask about repeating it under good conditions before you act on it. This is general planning information, not medical advice, a clinician should interpret your specific report alongside your history and hormones.

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Common questions

What is a normal sperm count?

By WHO 2021 reference limits, 16 million/mL concentration or 39 million total per ejaculate is the lower bound, drawn from the 5th percentile of recently-fertile men. Above it is reassuring; below it is worth a retest and a closer look, not an automatic diagnosis.

Is 4% normal morphology bad?

No, 4% is actually the WHO reference limit. Under strict criteria, most normal, fertile men have a low percentage of perfectly-shaped sperm, so a number around 4% is expected rather than alarming.

Should I retest if my first result is low?

Yes. Semen parameters vary a lot with abstinence, illness and handling, so most clinicians want at least two samples a few weeks apart before concluding anything. And any recent protocol change won't show for about 90 days.

More guides

Sources
  • World Health Organization. WHO laboratory manual for the examination and processing of human semen, 6th ed., 2021.
  • Liu PY et al. Rate, extent and modifiers of spermatogenic recovery in normal men after male hormonal contraception. The Lancet, 2006.

Prezerv is a self-guided planning tool. It does not provide medical advice, diagnosis, or treatment. Always consult a qualified clinician about your own situation.